Summer 2009 | |
Message from Stephanie West, Manager DePuy FUTURE LEADERS Program
Hello and welcome to another installment of the Future Leaders in Spine Surgery Newsletter! As always I hope you find this newsletter to be a valuable source of information.In this issue you will find an interesting clinical case presentation from Dr. Amer Samdani. Also, I had the opportunity to talk to Dr. David Shapiro from the Chicago area. We discussed his current clinical practice and how it’s changed as new technology becomes available. New to this issue is a section with a focus on neurosurgery specifically, the importance of neuro-monitoring for traumatic brain injury authored by Dr. Geoffrey Manley and Dr. Guy Rosenthal from the University of California, San Francisco. In regards to our educational activities this year, we recently held 3 FUTURE LEADERS educational programs. The “look back” section features highlights & photos from these meetings. And finally a reminder to those of you who have submitted an abstract for the 2008-2009 DePuy Spine Clinical Research Paper Challenge, the deadline for full paper submissions is fast approaching! June 30, 2009 is the deadline. I hope you enjoy this issue. To be a contributing author or to request content please feel free to contact me at any time. Swest03@its.jnj.com or 508 828-3680. Best regards, Stephanie SECTION I: Case discussion: Minimally Invasive Surgery for Adolescent Spinal Deformity Amer F. Samdani, MDShriner’s Hospital for Children, Philadelphia Dr. Samdani is a pediatric spine surgeon at the Shriner’s Hospital for Children in Philadelphia, PA. He is treating many of his patients using a minimally invasive surgical approach. The following is a case study featuring the use of minimally invasive surgery to treat a severe spinal deformity. History and Examination WC is a 12-year-old girl who presented to our institution with a Lenke 1AN 72 degree curve. She had originally presented with a 35 degree curve at age 9. MRI revealed no intraspinal anomalies. She progressed despite being braced in a TLSO for 16 hours/day. On physical examination her right shoulder was elevated, and on Adams forward bending test the inclinometer read 17 degrees. Neurological examination was within normal limits. Radiographic Studies Full length standing PA/lateral and bending films were obtained (Figure 1a-c). These demonstrated a right convex 72 degree curve from T5-L1, which bend down to 29 degrees. ![]() Operative Treatment The patient was brought to the operating room for a posterior spine fusion (PSF) utilizing a muscle sparing approach (Figure 2). After standard prep and drape, the fluoroscopy machine was used to plan a midline incision from T2-L2. The skin was opened sharply and undermined laterally maintaining fascial integrity. Under fluoroscopic guidance the Jamshidi needles were placed into the pedicle to a depth of 20 mm. This was done sequentially from L2-T2 bilaterally, skipping T4 on the right (Figure 3). Subsequently, guide wires were advanced with removal of the Jamshidi needles. At this point, the fluoroscopy machine was positioned for a lateral projection and a muscle protective sleeve passed over the guide wires. A cannulated awl was used to start the pedicle hole, followed by the appropriate size tap. At this point, each facet was visualized with a hand held retractor and the facets drilled with a high speed burr. Care was taken to ensure adequate decortication and the grafting material was placed. This consisted of a mixture of corticancellous chips, aspirated blood from the pedicle, and HEALOS Bone Graft Replacement. Subsequently, the appropriate size pedicle screw was inserted and the guide wire removed. ![]() Curve correction and derotation was performed by the 'rod second' technique as described by Vallespir et al.1 In this technique, vertebral coplanar alignment is attained by first placing two rods through the tubes on the convexity. Controlled, forceful separation of the rods results in coronal and axial correction. Once, the correction was attained an appropriately sized cobalt chrome rod bent into the appropriate sagittal contour was introduced on the concavity. The rod was inserted through L2 and sequentially up. Tactile and visual feedback guides the passing of the rod through the tubes. Once all tubes were engaged, set screws were placed and the rod reduced using reduction instruments. The concave rod was turned into the appropriate sagittal plane, and the set screws tightened. In a similar manner the rod on the convexity of the curve was placed. Prior to placement of the convex rod, an en bloc derotation maneuver was performed. Intraoperative x-rays confirmed good correction and the wound was closed in a standard manner. Intraoperative blood loss was 250 cc. The patient was discharged home on postoperative day 5. Her two month standing PA/lateral x-rays demonstrate her correction (Figure 4a,b). ![]() For the complete case report including references click on the following link SECTION I Amer Samdani's case report.pdf SECTION II: ASK THE EXPERT - The Evolution of Fusion TechnologiesInterview conducted by Stephanie West, DePuy Spine Manager, Medical Education David E. Shapiro, MDIllinois Bone & Joint Institute Dr. David Shapiro is a board-certified orthopaedic surgeon currently in private practice at the Illinois Bone & Joint Institute in Glenview, IL. Interview conducted by Stephanie West, DePuy Spine, Manager, Medical Education In this interview, Dr. Shapiro discusses how the evolution of fusion technologies has had an impact on his practice. SW: How has the evolution of spinal fusion technologies and techniques affected your practice over the past 10 years? DS: My indications for fusions have remained fairly constant over the past 10 years. The most common are spondylolisthesis, spinal stenosis with radiographic evidence of instability, recurrent disc herniation, stenosis and/or severe breakdown at a level adjacent to a previous fusion, and primary low back pain refractory to a year of conservative therapy.SW: How have these technologies benefited your patients? DS: Comparing the outcomes for both primary surgery and revision/secondary surgery patients who received PEEK vs. titanium rod implants - my PEEK patients (105) have markedly decreased postoperative pain in the short term which I attribute to the improved load sharing of the PEEK constructs. They were driving within 1-2 weeks, and were out of their braces within 4-6 weeks. Most were taking no pain medication other than TylenolSW: What are some of the key things you tell your patients when educating them about new spinal implant technologies such as PEEK rods? DS: I explain to my patients the material characteristics and potential benefits of load sharing or flexible rod fusion constructs and what they can expect regarding post-op pain and return to life, etc. I tell them that PEEK rods may help reduce post-operative pain due to 5 the reduced load that the rod places on the screw. The implants rarely have to come out due to residual pain. Not only that, I have achieved excellent fusion rates with them.SW: How do you think the use of PEEK rods will change your practice moving forward? DS: I suspect I will eventually move from 6.35 mm to 5.5 mm rod constructs. I like the idea of using the PEEK system in a percutaneous surgical approach. I recently used the VIPER ![]() SECTION III: A Look Ahead – Upcoming Education / EventsFor a complete look at the 2009 educational calendar please click on the following link:http://onlinespinecenter.com/ee/EducationEvents/CalendarofEvents/tabid/177/Default.aspx *For more information regarding DePuy Spine Medical Education events please contact the DePuy Spine Medical Education department at 1-800-741-8075 or visit our website at www.onlinespinecenter.com/ee SECTION III.I: A look "back": 2009 FUTURE LEADERS Educational events2009 DePuy Spine Fellows Spinal Deformity Summit: 1st annual meetingFebruary 6-7, 2009 Las Vegas, NV Chairmen: Munish Gupta, MD & Nathan Lebwohl, MD This past February the DePuy Spine Medical Education department hosted the 1st annual Spinal Deformity Summit at the Science Care facility in Las Vegas, NV. This program was offered to current spine fellows preparing to complete their fellowship this summer. Most of the attendees of this program had participated in the past FUTURE LEADERS educational programs starting with the 2008 Pre-fellowship Bioskills workshop. This goal of this program was to offer spine fellows the chance to learn surgical techniques in the area of adolescent idiopathic scoliosis and adult scoliosis. This course is an introductory training program designed to expose fellows to new treatment options for their patients with spinal deformities. Time was also set aside to cover topics related to socio-economic considerations including, contract negotiations with potential employers and billing and coding. ![]() March 5-7, 2009 Miami, FL Chairmen: Professor Alan Crockard, Robert Heary, MD, Brian Hoh, MD, Stephen Lewis, MD & Michael Wang, MD The 5th annual Neurosurgery Residents Education Summit was held on March 5-7, 2009 in Miami, FL. This year, 72 chief and senior neurosurgery residents attended the 2-day summit taught by 36 faculty including 5 chairmen. In prior years the Summit was limited to solely spinal surgery education. For the first time in 2009 the Summit included didactic and laboratory sessions covering both spinal and neurovascular surgical techniques. As in past years, topics related to practice management were also presented and well received. To read the full article please click on the following link: SECTION III.I - NeuroRes Summit09FINAL.pdf ![]() 2009 DePuy Spine Pre-fellowship Bioskills Workshop: 6th annual meeting May 15-16 & May 17-18, 2009 Denver, CO Chairmen: Carl Lauryssen, MD & Nathan Lebwohl The 6th annual DePuy Spine Pre-fellowship Bioskills Workshop was held in 2 sessions back-to-back the weekend of May 15-18, 2009. This program is designed to assist residents preparing to enter into a spine fellowship program with the transition. The faculty consists of fellowship directors from key institutions around the country. Many of the participants had the opportunity to work directly with their fellowship instructor prior to starting their fellowship. The course was attended in total by 50 incoming fellows and 25 faculty instructors. The course curriculum focused on the anatomy of the spine as well surgical techniques for anterior and posterior spine instrumentation. Upcoming FUTURE LEADERS Educational Programming: 2009 Advanced Concepts in Spine Arthroplasty and Minimally Invasive Surgery August 29-30, 2009 Chicago, IL Chairmen: Richard Guyer, MD, Nathan Lebwohl, MD & Michael Wang, MD 2009 Skills in Neurosurgery October 2-3, 2009 Phoenix, AZ Chairmen: Randall Porter, MD & Nicholas Theodore, MD For more information about these programs please contact Stephanie West in the DePuy Spine Medical Education department. SECTION IV: Neurosurgery Focus![]() ![]() Guy Rosenthal, MD and Geoffrey T. Manley, MD, PhD Department of Neurosurgery, University of California, San Francisco Geoffrey T. Manley, MD, PhD is the Chief of Neurosurgery at San Francisco General Hospital and Professor of Neurosurgery at the University of California San Francisco (UCSF). He is a trauma neurosurgeon with clinical interests in brain injury, spinal cord injury and neurocritical critical care. His translational research interests span from the laboratory to the bedside. Guy Rosenthal, MD is a clinical instructor and neurosurgical fellow at the University of California San Francisco (UCSF). The following is a case report authored by Dr. Rosenthal and Dr. Manley discussing the importance and the advances in neuromonitoring in patients who have suffered a severe traumatic brain injury. Overview Traumatic brain injury (TBI) remains a leading cause of death in young people. Monitoring and treating raised intracranial pressure following TBI is currently the main goal of therapeutic strategies in these patients. However, preventing secondary brain injury also requires ensuring adequate cerebral perfusion and oxygenation to the injured brain. In recent years our bedside cerebral monitoring capabilities in the Neurointensive Care Unit have progressed considerably. The recently revised Guidelines for the Management of Traumatic Brain Injury published by the Brain Trauma Foundation contain new recommendations that reflect these developments in Advanced Neuromonitoring. Previous editions of the Guidelines recommended maintaining CPP greater than 60 mm Hg in all adult severe TBI patients. Recent evidence suggests that patients with impaired autoregulation may have better outcomes when cerebral perfusion pressure (CPP) is maintained at lower levels (50-60 mmHg) compared with patients in whom autoregulation is intact, where higher CPP values (60-70 mmHg) are associated with improved outcome3. The newly-revised Brain Trauma Foundation Guidelines for the Treatment of Severe Traumatic Brain Injury incorporate the concept of differential CPP goals based on autoregulatory status1. The ability to assess cerebral autoregulation in severe TBI patients at bedside by a simple clinical test is thus becoming an important goal that can influence clinical care. The revised Guidelines indicate that Advanced Neuromonitoring can serve as an important adjunct in optimizing care in individual patients following severe TBI, suggesting monitoring of cerebral blood flow, oxygenation or metabolism to facilitate CPP management1. They also point out that Advanced Neuromonitoring can be useful when hyperventilation is employed as a therapeutic measure to treat elevated ICP2. At San Francisco General Hospital we incorporate Advanced Neuromonitoring as part of our routine monitoring protocol of severe TBI patients. In addition to ICP monitoring, patients are typically monitored with a Licox brain tissue oxygen tension (PbtO2) monitor, a jugular venous bulb monitor, and a HEMEDEX Cerebral Blood Flow (CBF) monitor. Part of our monitoring protocol involves performing bedside mean arterial pressure (MAP) challenges in severe TBI patients to assess cerebral autoregulation. When cerebral autoregulation is intact relatively large changes in mean arterial pressure do not lead to significant changes in cerebral blood flow. However, in some patients with brain injury cerebral autoregulation is disturbed. These patients are “pressure passive”, meaning that increases in MAP may lead to increased CBF, and conversely, a drop in MAP may lead to decreased CBF. Knowing whether an individual patient has intact cerebral autoregulation or is “pressure passive” can influence therapy. The new Guidelines for the Management of Severe TBI recommend a CPP goal of 50-70 mmHg and indicate that patients who have intact cerebral autoregulation will tolerate higher CPP values (up to 70 mmHg), while patients in whom autoregulation is impaired a lower CPP goal is appropriate (50-60 mmHg). In order to determine which patients have intact cerebral autoregulation and which patients do not, we initiate a controlled rise in MAP with a phenylephrine drip ("pressure challenge"). Our goal is to slowly raise MAP by 10-15 mmHg over a period of 10-20 minutes while monitoring CBF, ICP, and brain oxygenation. We closely monitor any changes in cerebral blood flow, ICP, and PbtO2 as MAP increases during the challenge. Patients with intact autoregulation will typically have only minimal changes in CBF, ICP, and PbtO2 during the MAP challenge. In contrast, those patients with impaired cerebral autoregulation respond with increased CBF and ICP as MAP rises. To read an illustrative case describing how the authors used the information derived from a pressure challenge in clinical care.
For Clinical Case Click Here Section V: Must Read Clinical ArticlesTo obtain a free copy of these articles simply click on the link below.Costs and state-specific rates of thoracic and lumbar vertebroplasty, 2001-2005 Gray, et al. SPINE 33:17, 1905-1912 2008 http://delivery.sheridan.com/downloads/mobile/LWW_143929_CP.exe Sterility of c-arm fluoroscopy during spinal surgery Biswas, et al SPINE 33:17 1913-1917 2008 http://delivery.sheridan.com/downloads/mobile/LWW_143932_CP.exe How accurately do novice surgeons place thoracic pedicle screws with the free-hand technique? Bergeson, et al SPINE 33:15 E501-E507 2008 http://delivery.sheridan.com/downloads/mobile/LWW_143931_CP.exe SECTION VI: DePuy Spine in the JournalsAs part of our commitment to further the clinical evidence in the spine community, we are proud to offer the following clinical research articles that further support the use of our products. To obtain a free copy of these articles simply click on the link below.Minimally Invasive Posterior Fixation Wang, et al. NEUROSURGERY 63:A197-A203, 2008 http://delivery.sheridan.com/downloads/mobile/LWW_152051_CP.exe Mini-open removal of extradural foraminal tumors of the lumbar spine Lu, D. et al. J Neurosurg Spine 10:46-50, 2009.> http://delivery.sheridan.com/downloads/mobile/JNS_151787_CP.exe Biomechanical evaluation and comparison of polyetheretherketone rod system to traditional titanium rod fixation Ponnappan, et al. The Spine Journal 9: 263-267, 2009. http://delivery.sheridan.com/downloads/mobile/ELS_151849_CP.exe Section VII: DePuy Spine NewsHEALOS
In April DePuy Spine, Inc. announced the launch of HEALOS Fx Injectable Bone Graft Replacement, the company’s first bone graft solution designed specifically for minimally invasive spine surgery (MIS). |